Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of genetic and environmental factors resulting in an aberrant activation of the mucosal immune system. This book contains a series of interdisciplinary discussions between clinical and basic scientists focusing on key issues such as: Epithelial cell and molecular biology, including apoptosis, necrosis and cell survival The role of bacterial milieu and mucosal bacteria in the IBD and of prebiotic and probiotic therapy The progress towards the identification of susceptibility genes and phenotype-determining genes The pharmacogenetics of IBD Mucosal immunology and therapeutic strategies stemming therefrom

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Inflammatory Bowel Disease

The Nature of Intelligence

Signalling Networks in Cell Shape and Motility

'In Silico' Simulation of Biological Processes

Purinergic Signalling in Neuron-Glia Interactions

Signalling Pathways in Acute Oxygen Sensing

Nuclear Organization in Development and Disease

Mammalian TRP Channels as Molecular Targets

Tissue Engineering of Cartilage and Bone

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Jamie A. Goode Inflammatory Bowel Disease

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