знания и навыки

научно-популярная литература

медицина / здравоохранение

зарубежная образовательная литература

медицина

The book «Drug Selectivity – An Evolving Concept in Medicinal Chemistry» provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.

юмористическая литература

фэнтези

современная русская литература

русское фэнтези

юмор и сатира

Drug Selectivity. An Evolving Concept in Medicinal Chemistry

This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final section focuses on intellectual property aspects during early clinical development. The emphasis throughout is on recent case studies to exemplify salient points, resulting in an abundance of practice-oriented information that is usually not available from other sources. Aimed at medicinal chemists in industry as well as academia, this invaluable reference enables readers to understand and navigate the challenges in developing clinical candidate molecules that can be successfully used in phase one clinical trials.

школьные учебники

учебная и научная литература

экономика

школьные учебники по географии

гуманитарные и общественные науки

науки о Земле

география

экономическая география

управление экономикой

Early Drug Development

боевики, остросюжетная литература

научная фантастика

боевая фантастика

боевики

Африка

будущее

стрелковое оружие

фантастический боевик

современные виды оружия

Drug Selectivity

Без серии

Helmut Buschmann