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Фармакология

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Phosphodiesterases and Their Inhibitors
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Phosphodiesterases and Their InhibitorsHugo Kubinyi
Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review…
Protein-Protein Interactions in Drug Discovery
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Protein-Protein Interactions in Drug DiscoveryHugo Kubinyi
Treating protein-protein interactions as a novel and highly promising class of drug targets, this vo…
Antiviral Drug Strategies
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Antiviral Drug StrategiesHugo Kubinyi
By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual …
Prodrugs and Targeted Delivery. Towards Better ADME Properties
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Prodrugs and Targeted Delivery. Towards Better ADME PropertiesHugo Kubinyi
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patent…
Virtual Screening. Principles, Challenges, and Practical Guidelines
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Virtual Screening. Principles, Challenges, and Practical GuidelinesHugo Kubinyi
Drug discovery is all about finding small molecules that interact in a desired way with larger molec…
Antibiotics. Targets, Mechanisms and Resistance
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Antibiotics. Targets, Mechanisms and ResistanceLetizia Brandi
Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms…
Natural Products in Medicinal Chemistry
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Natural Products in Medicinal ChemistryHugo Kubinyi
The inspiration provided by biologically active natural products to conceive of hybrids, congeners, …
Novel Antimicrobial Agents and Strategies
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Novel Antimicrobial Agents and StrategiesFrederick Harris
By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, resea…
Analogue-based Drug Discovery III
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Analogue-based Drug Discovery IIIJános Fischer
Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, neverthe…
Method Validation in Pharmaceutical Analysis. A Guide to Best Practice
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Method Validation in Pharmaceutical Analysis. A Guide to Best PracticeJoachim Ermer
This second edition of a global bestseller has been completely redesigned and extensively rewritten …
De novo Molecular Design
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De novo Molecular DesignGisbert Schneider
Systematically examining current methods and strategies, this ready reference covers a wide range of…
Transporters as Drug Targets
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Transporters as Drug TargetsGerd Folkers
As opposed to other books on the topic, this volume is unique in also covering emerging transporter …
Drug Metabolism Prediction
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Drug Metabolism PredictionHugo Kubinyi
The first professional reference on this highly relevant topic, for drug developers, pharmacologists…
Fusion Protein Technologies for Biopharmaceuticals. Applications and Challenges
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Fusion Protein Technologies for Biopharmaceuticals. Applications and ChallengesStefan R. Schmidt
The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most l…
Nonclinical Safety Assessment. A Guide to International Pharmaceutical Regulations
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Nonclinical Safety Assessment. A Guide to International Pharmaceutical RegulationsWilliam J. Brock
Bringing a new drug to market is a costly time-consuming process. Increased regional and internation…
Protein-Ligand Interactions
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Protein-Ligand InteractionsHugo Kubinyi
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressi…
Predictive Toxicology. From Vision to Reality
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Predictive Toxicology. From Vision to RealityHugo Kubinyi
Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this o…
Drug Discovery Toxicology. From Target Assessment to Translational Biomarkers
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Drug Discovery Toxicology. From Target Assessment to Translational BiomarkersYvonne Will
As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology…
Data Mining in Drug Discovery
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Data Mining in Drug DiscoveryHugo Kubinyi
Written for drug developers rather than computer scientists, this monograph adopts a systematic appr…
Scaffold Hopping in Medicinal Chemistry
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Scaffold Hopping in Medicinal ChemistryHugo Kubinyi
This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of …
Targeted Biomarker Quantitation by LC-MS
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Targeted Biomarker Quantitation by LC-MSNaidong Weng
The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomar…
Reactive Drug Metabolites
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Reactive Drug MetabolitesHugo Kubinyi
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is b…
Thermodynamics and Kinetics of Drug Binding
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Thermodynamics and Kinetics of Drug BindingHugo Kubinyi
This practical reference for medicinal and pharmaceutical chemists combines the theoretical backgrou…
Biological Drug Products. Development and Strategies
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Biological Drug Products. Development and StrategiesWei Wang
Tested and proven solutions to the challenges of biological drug product development Biological drug…
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